Penalized regression methods in genetic research

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Penalized Estimators in Cox Regression Model

The proportional hazard Cox regression models play a key role in analyzing censored survival data. We use penalized methods in high dimensional scenarios to achieve more efficient models. This article reviews the penalized Cox regression for some frequently used penalty functions. Analysis of medical data namely ”mgus2” confirms the penalized Cox regression performs better than the cox regressi...

متن کامل

Penalized Regression Methods for Linear Models in SAS/STAT

Regression problems with many potential candidate predictor variables occur in a wide variety of scientific fields and business applications. These problems require you to perform statistical model selection to find an optimal model, one that is as simple as possible while still providing good predictive performance. Traditional stepwise selection methods, such as forward and backward selection...

متن کامل

Optimized application of penalized regression methods to diverse genomic data

MOTIVATION Penalized regression methods have been adopted widely for high-dimensional feature selection and prediction in many bioinformatic and biostatistical contexts. While their theoretical properties are well-understood, specific methodology for their optimal application to genomic data has not been determined. RESULTS Through simulation of contrasting scenarios of correlated high-dimens...

متن کامل

Penalized least squares regression methods and applications to neuroimaging

The goals of this paper are to review the most popular methods of predictor selection in regression models, to explain why some fail when the number P of explanatory variables exceeds the number N of participants, and to discuss alternative statistical methods that can be employed in this case. We focus on penalized least squares methods in regression models, and discuss in detail two such meth...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: OA Genetics

سال: 2013

ISSN: 2054-197X

DOI: 10.13172/2054-197x-1-1-920